Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.33 |
| ▸ | MARS1 | P56192 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24075634 | 0.92 | DOT1L (0.37) | SLC29A1FGFR1FGFR4PIK3CDABL1 | |
| SCHEMBL31028254 | 0.91 | P2RX3 (0.39) | SLC29A1FGFR1FGFR4NT5EPTGER1 | |
| SCHEMBL24075629 | 0.89 | EP300 (0.36) | SLC29A1FGFR1FGFR4NT5EPTGER1 | |
| SCHEMBL24075511 | 0.86 | MARS1 (0.41) | MARS1PIK3CDEGFRPI4KB | |
| SCHEMBL31028216 | 0.86 | MARS1 (0.41) | MARS1PIK3CDEGFRPI4KB | |
| SCHEMBL28821449 | 0.85 | P2RX3 (0.36) | SLC29A1FGFR1FGFR4P2RX3PIK3CD | |
| SCHEMBL29727327 | 0.85 | P2RX3 (0.36) | SLC29A1FGFR1FGFR4P2RX3PIK3CD | |
| SCHEMBL24075627 | 0.85 | P2RX3 (0.36) | SLC29A1FGFR1FGFR4P2RX3PIK3CD | |
| SCHEMBL24075523 | 0.82 | DOT1L (0.35) | SLC29A1FGFR1FGFR4MARS1PDE4A | |
| SCHEMBL24074732 | 0.81 | SLC29A1 (0.35) | SLC29A1FGFR1FGFR4PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239077-A1 | MLL1 INHIBITORS AND ANTI-CANCER AGENTS | NOVARTIS AG (CH) | 2021-12-02 | — | — | WO | disclosed |