Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FOS | P01100 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24090477 | 0.92 | ADORA3 (0.37) | HPGDKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL24075080 | 0.85 | HPGD (0.45) | HPGDKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL24075081 | 0.84 | HPGD (0.44) | HPGDKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL22857912 | 0.84 | ALDH1A1 (0.40) | HPGDKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL24075874 | 0.83 | HPGD (0.37) | HPGDKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL24075686 | 0.82 | NR1H2 (0.43) | HPGDKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL24075089 | 0.81 | KDM4E (0.44) | HPGDKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL24075715 | 0.78 | NPC1 (0.47) | HPGDKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL25206930 | 0.77 | HTT (0.43) | HPGDKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL22858078 | 0.74 | NPC1 (0.41) | HPGDKDM4ESMN1; SMN2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312356-B2 | Anthelmintic heterocyclic compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2025-05-27 | — | — | US | disclosed |
| US-20240166653-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-05-23 | — | — | US | disclosed |
| US-11964977-B2 | Anthelmintic heterocyclic compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2024-04-23 | — | — | US | disclosed |
| EP-4185589-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| US-20210380591-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-09 | — | — | US | disclosed |
| US-20210380591-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-09 | — | — | US | disclosed |
| WO-2021242581-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-02 | — | — | WO | disclosed |
| WO-2021242581-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964977-B2 | Anthelmintic heterocyclic compounds | AADAC, HNMT, HRH4 | HPGD 185/4885KDM4E 956/4885SMN1; SMN2 3947/4885 |
| US-20240166653-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | AADAC, HNMT, HRH4 | HPGD 185/4885KDM4E 956/4885SMN1; SMN2 3947/4885 |
| US-12312356-B2 | Anthelmintic heterocyclic compounds | AADAC, HNMT, HRH4 | HPGD 185/4885KDM4E 956/4885SMN1; SMN2 3947/4885 |
| US-20210380591-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | AADAC, HNMT, HRH4 | HPGD 185/4885KDM4E 956/4885SMN1; SMN2 3947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.