Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31754855 | 0.90 | F2 (0.37) | CHRM5USP2HTR6PTGER2PKM | |
| SCHEMBL1157010 | 0.89 | HTR6 (0.41) | CHRM5HTR6ALDH1A1PKM | |
| SCHEMBL30089413 | 0.88 | HTR2C (0.36) | HTR6PKMHDAC1 | |
| SCHEMBL1156487 | 0.88 | HTR2C (0.36) | HDAC1MET | |
| SCHEMBL30089406 | 0.88 | F2 (0.37) | CHRM5USP2HTR6PTGER2ALDH1A1 | |
| SCHEMBL1156621 | 0.88 | HTR2C (0.42) | HTR6 | |
| SCHEMBL31755377 | 0.87 | SMPD1 (0.37) | HTR6ALDH1A1 | |
| SCHEMBL1156562 | 0.87 | HTR6 (0.40) | HTR6ALDH1A1 | |
| SCHEMBL2416549 | 0.87 | RIPK1 (0.39) | HTR6ALDH1A1PKM | |
| SCHEMBL30089348 | 0.87 | HTR6 (0.40) | HTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894801-A | Pyrrole sulfonyl derivative, and preparation method and application thereof | 天地恒一制药股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |