SCHEMBL30089413

SCHEMBL30089413

CN(Cc1cc(Br)n(S(=O)(=O)c2cccc(O)c2)c1)C(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.36
SLC6A4 P31645 2/20 0.36
HTR6 P50406 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
HDAC1 Q13547 2/20 0.34
HDAC6 Q9UBN7 2/20 0.34
HDAC2 Q92769 1/20 0.34
GLS O94925 1/20 0.34
MMP2 P08253 1/20 0.34
NQO2 P16083 1/20 0.34
PKM P14618 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD17B1 P14061 3/20 0.33
HSD17B2 P37059 3/20 0.33
RIPK1 Q13546 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1156487 0.90 HTR2C (0.36) HTR2CSLC6A4HDAC1HDAC6HDAC2
SCHEMBL1156621 0.90 HTR2C (0.42) HTR2CSLC6A4HTR6GLS
SCHEMBL30089348 0.89 HTR6 (0.40) HTR2CSLC6A4HTR6RIPK1
SCHEMBL1156562 0.89 HTR6 (0.40) HTR2CSLC6A4HTR6RIPK1
SCHEMBL2416549 0.89 RIPK1 (0.39) HTR2CSLC6A4HTR6PKMRIPK1
SCHEMBL2407643 0.88 CHRM5 (0.42) HTR6HDAC1PKM
SCHEMBL4411752 0.88 HTR2C (0.41) HTR2CSLC6A4HTR6GLS
SCHEMBL31754845 0.87 RORC (0.42) HTR6
SCHEMBL29262658 0.86 TNFSF11 (0.46) L3MBTL1MMP2
SCHEMBL30894736 0.85 HTR2C (0.38) HTR2CSLC6A4HTR6GLSMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001864-A1 COMPOUND CONTAINING SULFAMIDE STRUCTURE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF, AND PHARMACEUTICAL COMPOSITION AND APPLICATION NANJING SHUOHUI PHARMATECHNOLOGY CO., LTD (CN) 2026-01-01 US disclosed
WO-2023284159-A1 COMPOUND CONTAINING SULFAMIDE STRUCTURE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF, AND PHARMACEUTICAL COMPOSITION AND APPLICATION 南京烁慧医药科技有限公司 2023-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001864-A1 COMPOUND CONTAINING SULFAMIDE STRUCTURE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF, AND PHARMACEUTICAL COMPOSITION AND APPLICATION SLC10A2, SLC6A11, ABCB11 HTR2C 663/4885SLC6A4 79/4885HTR6 887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.