SCHEMBL24076563

SCHEMBL24076563

O=C(NCCN1CCC(Cc2ccccc2)CC1)c1cc2cc3c(cc2[nH]1)OCCO3

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 6/20 0.67
SLC6A4 P31645 5/20 0.67
KDM4E B2RXH2 2/20 0.54
HSD17B10 Q99714 2/20 0.54
ALDH1A1 P00352 2/20 0.54
ACHE P22303 1/20 0.53
BACE1 P56817 1/20 0.53
PARP1 P09874 1/20 0.52
SLC6A3 Q01959 1/20 0.51
TMEM97 Q5BJF2 2/20 0.50
CCR3 P51677 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24075745 0.94 SLC6A2 (0.67) SLC6A2SLC6A4KDM4EHSD17B10ALDH1A1
SCHEMBL30301405 0.87 SLC6A2 (0.71) SLC6A2SLC6A4KDM4EHSD17B10ALDH1A1
SCHEMBL27015989 0.87 SLC6A2 (0.71) SLC6A2SLC6A4KDM4EHSD17B10ALDH1A1
SCHEMBL27015752 0.86 SLC6A2 (0.70) SLC6A2SLC6A4KDM4EHSD17B10ALDH1A1
SCHEMBL30301396 0.86 SLC6A2 (0.70) SLC6A2SLC6A4KDM4EHSD17B10ALDH1A1
SCHEMBL27015546 0.86 SLC6A2 (0.70) SLC6A2SLC6A4KDM4EHSD17B10ALDH1A1
SCHEMBL30301376 0.86 SLC6A2 (0.70) SLC6A2SLC6A4KDM4EHSD17B10ALDH1A1
SCHEMBL27016437 0.86 SLC6A2 (0.89) SLC6A2SLC6A4KDM4EHSD17B10ALDH1A1
SCHEMBL27008240 0.84 SLC6A2 (0.73) SLC6A2SLC6A4KDM4EHSD17B10ALDH1A1
SCHEMBL30301407 0.84 ACHE (0.75) SLC6A2SLC6A4KDM4EACHEBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018119-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2024-01-18 US disclosed
WO-2021241876-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS 재단법인 대구경북첨단의료산업진흥재단 2021-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018119-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS MAOA, DRD2, MAOB SLC6A2 4/4885SLC6A4 23/4885KDM4E 693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.