Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21082263 | 0.79 | CHRM5 (0.43) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL1385192 | 0.78 | MEN1 (0.39) | CHRM5CHRM3SIGMAR1LMNAMEN1 | |
| SCHEMBL21235725 | 0.77 | SMN1; SMN2 (0.54) | CHRM5CHRM3SMN1; SMN2POLBLMNA | |
| SCHEMBL18735945 | 0.74 | MGLL (0.38) | POLBSIGMAR1LMNAPHGDHALDH1A1 | |
| SCHEMBL20459374 | 0.73 | — | — | |
| SCHEMBL872595 | 0.73 | USP2 (0.46) | SMN1; SMN2HSD17B10LMNAPHGDHALDH1A1 | |
| SCHEMBL15224399 | 0.72 | SMN1; SMN2 (0.41) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL154268 | 0.70 | SMN1; SMN2 (0.56) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL10667505 | 0.70 | SMN1; SMN2 (0.56) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL1393824 | 0.70 | SMN1; SMN2 (0.56) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11191769-B2 | Fused thiophene compounds | BIOTHERYX, INC. (US) | 2021-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11191769-B2 | Fused thiophene compounds | SSB, ICAM1, VCAM1 | CHRM5 4458/4885CHRM3 4310/4885SMN1; SMN2 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.