SCHEMBL15224399

SCHEMBL15224399

C1CN(CSSCN2CCNCC2)CCN1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
POLB P06746 1/20 0.41
HSD17B10 Q99714 1/20 0.40
CXCR4 P61073 4/20 0.39
SIGMAR1 Q99720 5/20 0.38
CHRM5 P08912 3/20 0.38
CHRM3 P20309 3/20 0.38
CHRM2 P08172 2/20 0.34
CHRM1 P11229 2/20 0.34
MEN1 O00255 1/20 0.34
ADRA2C P18825 1/20 0.34
CCR2 P41597 1/20 0.34
CXCL12 P48061 1/20 0.34
BLM P54132 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3096045 0.83 POLB (0.33) SMN1; SMN2POLBHSD17B10CXCR4SIGMAR1
SCHEMBL20459374 0.78
SCHEMBL25668133 0.78
SCHEMBL20980235 0.78
SCHEMBL150591 0.73
SCHEMBL3537892 0.73
SCHEMBL24079207 0.72 CHRM5 (0.44) SMN1; SMN2POLBHSD17B10CXCR4SIGMAR1
SCHEMBL10724711 0.72 HSD17B10 (0.38) SMN1; SMN2POLBHSD17B10CXCR4SIGMAR1
SCHEMBL24532104 0.72 SIGMAR1 (0.41) SMN1; SMN2POLBHSD17B10CXCR4SIGMAR1
SCHEMBL1904154 0.72 POLB (0.48) SMN1; SMN2POLBHSD17B10CXCR4SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023126969-A1 ORAL FILMS OF ANIT-PARASITIC DRUGS LAURUS LABS LIMITED (IN) 2023-07-06 WO disclosed
CN-111771885-B Pest control composition comprising novel iminopyridine derivatives 株式会社MMAG 2022-05-17 CN disclosed
EP-3694489-A2 METHODS AND COMPOSITIONS FOR TOPICAL DELIVERY Illustris Pharmaceuticals, Inc. (US) 2020-08-19 EP disclosed
CN-110256336-A Nitogen-contained heterocycle derivant with 2- imino group and the pest control agent comprising it 明治制果药业株式会社 2019-09-20 CN disclosed
CN-109705032-A Nitogen-contained heterocycle derivant with 2- imino group and the pest control agent comprising it 明治制果药业株式会社 2019-05-03 CN disclosed
WO-2019075263-A2 METHODS AND COMPOSITIONS FOR TOPICAL DELIVERY ILLUSTRIS PHARMACEUTICALS, INC. (US) 2019-04-18 WO disclosed
US-20190105261-A1 METHODS AND COMPOSITIONS FOR TOPICAL DELIVERY ILLUSTRIS PHARMACEUTICALS, INC. 2019-04-11 US disclosed
EP-3442488-A1 COMPOSITIONS FOR TOPICAL APPLICATION OF COMPOUNDS Illustris Pharmaceuticals, Inc. (US) 2019-02-20 EP disclosed
US-20190008795-A1 COMPOSITIONS FOR TOPICAL APPLICATION OF COMPOUNDS ILLUSTRIS PHARMACEUTICALS, INC. 2019-01-10 US disclosed
US-20180042233-A1 NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE HAVING 2-IMINO GROUP AND PEST CONTROL AGENT INCLUDING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2018-02-15 US disclosed
WO-2017180788-A1 COMPOSITIONS FOR TOPICAL APPLICATION OF COMPOUNDS ILLUSTRIS PHARMACEUTICALS, INC. (US) 2017-10-19 WO disclosed
US-20170290778-A1 COMPOSITIONS FOR TOPICAL APPLICATION OF COMPOUNDS ILLUSTRIS PHARMACEUTICALS, INC. 2017-10-12 US disclosed
EP-2634174-B1 Nitrogen-containing heterocyclic derivate having 2-imino group and pest control agent including the same MEIJI SEIKA PHARMA CO LTD (JP) 2017-05-17 EP disclosed
US-20150005347-A1 NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE HAVING 2-IMINO GROUP AND PEST CONTROL AGENT INCLUDING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2015-01-01 US disclosed
CN-104220424-A Nitrogen-containing heterocyclic derivative having 2-imino group and pest control agent comprising the same MEIJI SEIKA PHARMA CO LTD 2014-12-17 CN disclosed
WO-2013129692-A2 NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE HAVING 2-IMINO GROUP AND PEST CONTROL AGENT INCLUDING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2013-09-06 WO disclosed
EP-2634174-A2 Nitrogen-containing hetercyclic derivate having 2-imino group and pest control agent including the same Meiji Seika Pharma Co., Ltd. (JP) 2013-09-04 EP disclosed
CN-85109721-A Preparation has the ectoparasite of the no disease homoiothermic animal of control and the method for endoparasite compositions 1987-07-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180042233-A1 NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE HAVING 2-IMINO GROUP AND PEST CONTROL AGENT INCLUDING THE SAME CBR1, CBR3, NIT2 SMN1; SMN2 2174/4885POLB 3786/4885HSD17B10 1105/4885
US-20150005347-A1 NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE HAVING 2-IMINO GROUP AND PEST CONTROL AGENT INCLUDING THE SAME CBR1, CBR3, NIT2 SMN1; SMN2 2174/4885POLB 3786/4885HSD17B10 1105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.