SCHEMBL24079241

SCHEMBL24079241

c1ccc2cc3c(cc2c1)c1ccccc1n3-c1ccc2cc3c4ccccc4n(-c4cccc5cc(-c6nc7ccccc7nc6-c6ccc7ccc8ccccc8c7c6)ccc45)c3cc2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.36
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 1/20 0.32
HIF1A Q16665 1/20 0.32
CYP1B1 Q16678 1/20 0.32
HSD17B10 Q99714 1/20 0.32
F2 P00734 1/20 0.32
F10 P00742 1/20 0.32
PRSS1 P07477 1/20 0.32
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HPGD P15428 1/20 0.30
PDPK1 O15530 2/20 0.30
HTR6 P50406 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30
TUBB4A P04350 1/20 0.30
TUBB P07437 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21716687 1.00 GSR (0.36) GSRTDP1ALDH1A1HIF1ACYP1B1
SCHEMBL21716919 0.95 GSR (0.34) GSRTDP1
SCHEMBL21716766 0.94 GSR (0.34) GSRTDP1PDPK1
SCHEMBL21716277 0.94 ALDH1A1 (0.33) GSRALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL21716728 0.93 F2 (0.33) GSRALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL21716689 0.93 F2 (0.33) GSRALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL21716857 0.91 GSR (0.37) GSRTDP1HTR6
SCHEMBL21716279 0.91 GSR (0.37) GSRTDP1HTR6
SCHEMBL21717674 0.91 PDPK1 (0.32) F2F10PRSS1PDPK1
SCHEMBL21716956 0.88 L3MBTL1 (0.36) TDP1ALDH1A1HIF1ACYP1B1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11192884-B2 Heterocyclic compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2021-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11192884-B2 Heterocyclic compound and organic light-emitting device comprising same CYP1A1, CYP1B1, CRY1 GSR 3951/4885TDP1 1382/4885ALDH1A1 33/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.