Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351005 | 0.82 | ACHE (0.57) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL23876585 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL24079254 | 0.81 | L3MBTL1 (0.47) | KDM4EALDH1A1TDP1CYP1A2CYP2C19 | |
| SCHEMBL23876693 | 0.80 | KDM4E (0.82) | KDM4EALDH1A1TDP1HTR7SMN1; SMN2 | |
| SCHEMBL13433991 | 0.79 | POLB (0.46) | KDM4EALDH1A1TDP1CYP1A2CYP2C19 | |
| SCHEMBL10493570 | 0.79 | ALDH1A1 (0.84) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL13232444 | 0.79 | L3MBTL1 (0.61) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL21079236 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1TDP1GAASMN1; SMN2 | |
| SCHEMBL14000157 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1TDP1CYP1A2CYP2D6 | |
| SCHEMBL13019317 | 0.78 | MAPT (0.47) | KDM4EALDH1A1TDP1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192886-B2 | S1P1 agonist and application thereof | MEDSHINE DISCOVERY INC. (CN) | 2021-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192886-B2 | S1P1 agonist and application thereof | S1PR1, S1PR2, S1PR3 | KDM4E 3986/4885ALDH1A1 2418/4885TDP1 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.