Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414877 | 0.82 | KMT2A (0.39) | ADORA2AALDH1A1SMN1; SMN2MAPTPKM | |
| SCHEMBL2409139 | 0.81 | PDE4A (0.41) | ADORA2AALDH1A1SMN1; SMN2PKMMETAP1 | |
| SCHEMBL2409883 | 0.80 | KMT2A (0.38) | ADORA2AALDH1A1SMN1; SMN2MAPTPKM | |
| SCHEMBL2413283 | 0.77 | BRD4 (0.35) | ADORA2AALDH1A1SMN1; SMN2MAPTPKM | |
| SCHEMBL31045060 | 0.74 | METAP1 (0.59) | ADORA2ASMN1; SMN2ADORA1METAP1HTR2C | |
| SCHEMBL14112790 | 0.74 | METAP1 (0.59) | ADORA2ASMN1; SMN2ADORA1METAP1HTR2C | |
| SCHEMBL2408334 | 0.73 | KRAS (0.60) | ALDH1A1SMN1; SMN2MAPTPKMNPC1 | |
| SCHEMBL9026739 | 0.69 | KDM4E (0.46) | ADORA2AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL9027654 | 0.69 | BRD4 (0.45) | ADORA2AALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2414783 | 0.68 | BRD4 (0.35) | ADORA2AALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539338-A1 | NOVEL MICROBICIDES | Syngenta Participations AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| US-20120316184-A1 | NOVEL MICROBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-13 | — | — | US | disclosed |
| CN-102770433-A | Novel microbicides | SYNGENTA PARTICIPATIONS A G | 2012-11-07 | — | — | CN | disclosed |
| WO-2011104183-A1 | NOVEL MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316184-A1 | NOVEL MICROBICIDES | NOX1, MSR1, FPR1 | ADORA2A 1826/4885ALDH1A1 116/4885SMN1; SMN2 3707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.