Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.34 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409883 | 0.89 | KMT2A (0.38) | KMT2ASMN1; SMN2ALDH1A1MAPTPKM | |
| SCHEMBL2407988 | 0.82 | ADORA2A (0.43) | SMN1; SMN2ALDH1A1MAPTPKMADORA2A | |
| SCHEMBL3787489 | 0.82 | MAPT (0.50) | KMT2AALDH1A1MAPTMAPK1NR1I3 | |
| SCHEMBL8142539 | 0.76 | MAPT (0.48) | KMT2ASMN1; SMN2ALDH1A1MAPTCYP1A2 | |
| SCHEMBL14241615 | 0.75 | PDE7A (0.39) | KMT2AALDH1A1ADORA2AMAPK1RAB9A | |
| SCHEMBL8779574 | 0.74 | MAPK1 (0.62) | KMT2AALDH1A1MAPTMAPK1NR1I3 | |
| SCHEMBL2413283 | 0.74 | BRD4 (0.35) | SMN1; SMN2ALDH1A1MAPTPKMADORA2A | |
| SCHEMBL2408334 | 0.71 | KRAS (0.60) | KMT2ASMN1; SMN2ALDH1A1MAPTPKM | |
| SCHEMBL8779414 | 0.70 | MEN1 (0.54) | KMT2AALDH1A1MAPTBRD4CYP1A2 | |
| SCHEMBL8779415 | 0.70 | MAPT (0.53) | KMT2AALDH1A1MAPTBRD4NR1I3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539338-A1 | NOVEL MICROBICIDES | Syngenta Participations AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| US-20120316184-A1 | NOVEL MICROBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-13 | — | — | US | disclosed |
| WO-2011104183-A1 | NOVEL MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316184-A1 | NOVEL MICROBICIDES | NOX1, MSR1, FPR1 | KMT2A 4364/4885SMN1; SMN2 3707/4885ALDH1A1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.