Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 2/20 | 0.60 |
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409597 | 0.78 | KRAS (0.67) | KRASSPRPDE5AKMT2AALDH1A1 | |
| SCHEMBL10718384 | 0.77 | KMT2A (0.61) | KRASPDE5AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL26676961 | 0.76 | KRAS (1.00) | KRASSPRPDE5AKMT2AALDH1A1 | |
| SCHEMBL28533431 | 0.75 | KRAS (0.65) | KRASSPRPDE5AKMT2AALDH1A1 | |
| SCHEMBL2407988 | 0.73 | ADORA2A (0.43) | KRASALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2414877 | 0.71 | KMT2A (0.39) | KMT2AALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2409883 | 0.69 | KMT2A (0.38) | PDE5AKMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2202679 | 0.68 | PDE5A (0.59) | KRASSPRPDE5AKMT2AALDH1A1 | |
| SCHEMBL27965909 | 0.68 | PDE5A (0.62) | KRASSPRPDE5AKMT2AALDH1A1 | |
| SCHEMBL2413283 | 0.68 | BRD4 (0.35) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539338-A1 | NOVEL MICROBICIDES | Syngenta Participations AG (CH) | 2013-01-02 | — | — | EP | disclosed |
| US-20120316184-A1 | NOVEL MICROBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-13 | — | — | US | disclosed |
| CN-102770433-A | Novel microbicides | SYNGENTA PARTICIPATIONS A G | 2012-11-07 | — | — | CN | disclosed |
| WO-2011104183-A1 | NOVEL MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316184-A1 | NOVEL MICROBICIDES | NOX1, MSR1, FPR1 | KRAS 1691/4885SPR 2751/4885PDE5A 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.