Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26473856 | 0.85 | TRPA1 (0.39) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL19382047 | 0.77 | HDAC8 (0.41) | CYP1A2RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25665126 | 0.76 | TRPA1 (0.43) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL4905317 | 0.75 | TRPA1 (0.43) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL14303655 | 0.75 | LMNA (0.37) | CYP1A2CYP2A6ALDH1A1MAPTLMNA | |
| SCHEMBL14345794 | 0.75 | TRPA1 (0.59) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL12966316 | 0.73 | LMNA (0.33) | SMN1; SMN2ALDH1A1LMNAKCNH2HRH3 | |
| SCHEMBL17177427 | 0.73 | ALDH1A1 (0.35) | RAB9ASMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL8222799 | 0.73 | NPC1 (0.43) | TRPA1CYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL13754339 | 0.72 | TRPA1 (0.40) | TRPA1CYP1A2CYP2A6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919056-A1 | COMPOUNDS AND USES THEREOF FOR THE MODULATION OF HEMOGLOBIN | Global Blood Therapeutics, Inc. (US) | 2021-12-08 | — | — | EP | disclosed |