Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.53 |
| ▸ | PTGIR | P43119 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240822 | 0.89 | KDM4E (0.74) | KDM4EPOLBPTGS1AKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL2022863 | 0.87 | KDM4E (0.72) | KDM4EPOLBPTGS1AKR1C3AKR1C2 | |
| SCHEMBL27952524 | 0.87 | KDM4E (0.72) | KDM4EPOLBPTGS1AKR1C3AKR1C2 | |
| Hydrogen Sulfide SCHEMBL29062416 | 0.87 | KDM4E (0.72) | KDM4EPOLBPTGS1AKR1C3AKR1C2 | |
| SCHEMBL13464286 | 0.85 | CA2 (0.60) | KDM4EPOLBPTGS1CYP26A1HTT | |
| SCHEMBL10919957 | 0.85 | PTGIR (0.54) | HTTCTBP2PTGIRSMN1; SMN2MAPT | |
| SCHEMBL9468432 | 0.84 | KDM4E (0.68) | KDM4EPOLBPTGS1AKR1C3AKR1C2 | |
| SCHEMBL4217510 | 0.84 | KDM4E (0.68) | KDM4EPOLBPTGS1AKR1C3AKR1C2 | |
| Dimethylamine SCHEMBL1630099 | 0.84 | KDM4E (0.73) | KDM4EPOLBPTGS1AKR1C3AKR1C2 | |
| SCHEMBL3468140 | 0.81 | SRD5A2 (0.68) | KDM4EPOLBPTGS1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086079-B1 | DERIVATIVES OF HYDROXYPHENYLSULFANYLBENZOIC AND HYDROXYPHENYLSULFANYLARYLACETIC ACIDS | LECIVA A S (CZ) | 2003-05-07 | — | — | EP | disclosed |
| US-6303612-B1 | USED AS ANTIINFLAMMATORY AND/OR ANTIASTHMATIC AGENTS | LECIVA, A.S. (CZ) | 2001-10-16 | — | — | US | disclosed |