Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | IDE | P14735 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2415722 | 0.90 | PTGDR2 (0.35) | SLC1A3SLC1A2SLC1A1DYRK1A | |
| SCHEMBL2416815 | 0.88 | GRM4 (0.33) | — | |
| SCHEMBL2417456 | 0.88 | PLCG1 (0.30) | — | |
| SCHEMBL2418766 | 0.88 | PTGDR (0.35) | IDE | |
| SCHEMBL1278409 | 0.87 | PTGDR2 (0.32) | — | |
| SCHEMBL2412871 | 0.87 | PTGDR2 (0.42) | — | |
| SCHEMBL1278109 | 0.87 | FPR1 (0.34) | SLC1A3SLC1A2SLC1A1BACE1 | |
| SCHEMBL2412419 | 0.86 | GRM4 (0.39) | — | |
| SCHEMBL2411975 | 0.86 | ABCC9 (0.32) | — | |
| SCHEMBL2413126 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |