Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412419 | 0.94 | GRM4 (0.39) | PTGDR2CCKARGRM4MMP2MMP9 | |
| SCHEMBL2416815 | 0.92 | GRM4 (0.33) | PTGDR2CCKARALDH3A1GRM4MMP2 | |
| SCHEMBL2415722 | 0.91 | PTGDR2 (0.35) | PTGDR2CCKARMMP2MMP9MMP8 | |
| SCHEMBL2418766 | 0.91 | PTGDR (0.35) | PTGDR2HTR6 | |
| SCHEMBL1278409 | 0.90 | PTGDR2 (0.32) | PTGDR2CCKARMMP2MMP9MMP8 | |
| SCHEMBL1278109 | 0.88 | FPR1 (0.34) | PTGDR2 | |
| SCHEMBL2409151 | 0.88 | ALDH1A1 (0.34) | PTGDR2CCKARPDE4ANAMPT | |
| SCHEMBL2412112 | 0.87 | KAT6A (0.32) | PTGDR2CCKARNAMPT | |
| SCHEMBL2413126 | 0.87 | — | — | |
| SCHEMBL2408353 | 0.87 | SLC1A3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |