Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760898 | 0.86 | CLK4 (0.50) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19579216 | 0.86 | ADRA2C (0.47) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19579268 | 0.85 | GABRG2 (0.51) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16127479 | 0.84 | CLK4 (0.52) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3172854 | 0.83 | CLK4 (0.56) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21929166 | 0.82 | IDO1 (0.55) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28160268 | 0.81 | TRPA1 (0.47) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL18255785 | 0.81 | GABRG2 (0.43) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2154026 | 0.80 | CLK4 (0.65) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19579116 | 0.80 | ADRA2C (0.54) | CLK4GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452471-B1 | ORGANIC MOLECULES, ESPECIALLY FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2021-12-08 | — | — | EP | disclosed |