SCHEMBL24086099

SCHEMBL24086099

CCCCCCN(N)c1nc2ccc(F)cc2s1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ GFER P55789 2/20 0.47
▸ AXL P30530 1/20 0.47
▸ MAPT P10636 3/20 0.44
▸ LMNA P02545 2/20 0.44
▸ ALDH1A1 P00352 4/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ RAD52 P43351 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ PKM P14618 1/20 0.43
▸ ALOX12 P18054 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ NPC1 O15118 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ HTT P42858 2/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.41
▸ APP P05067 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376668 0.91 RAD52 (0.39) GFERAXLMAPTLMNAALDH1A1
SCHEMBL28683905 0.85 MAPT (0.48) MAPTALDH1A1KMT2AMEN1KDM4E
SCHEMBL29379396 0.85 MAPT (0.48) MAPTALDH1A1KMT2AMEN1KDM4E
SCHEMBL15722637 0.82 NPC1 (0.50) GFERLMNAALDH1A1KDM4ENPC1
SCHEMBL16705693 0.82 NPC1 (0.50) GFERLMNAALDH1A1KDM4ENPC1
SCHEMBL23185863 0.82 NPC1 (0.50) GFERLMNAALDH1A1KDM4ENPC1
SCHEMBL15722747 0.82 NPC1 (0.50) GFERLMNAALDH1A1KDM4ENPC1
SCHEMBL24086123 0.82 CYP1A2 (0.51) LMNAALDH1A1KMT2AMEN1KDM4E
SCHEMBL24086107 0.81 ALDH1A1 (0.56) MAPTLMNAALDH1A1KMT2AMEN1
SCHEMBL18369556 0.81 NPC1 (0.51) GFERLMNAALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230137250-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2023-05-04 — — US disclosed
US-20230137250-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2023-05-04 — — US disclosed
US-11560518-B2 Polymerizable liquid crystal compound, polymerizable composition, polymer, retardation film, method for producing retardation film, transfer laminate, optical member, method for producing optical member, and display device DAI NIPPON PRINTING CO., LTD. (JP) 2023-01-24 — — US disclosed
US-20210380884-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2021-12-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230137250-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE TRRAP, CDH1, LRRFIP1 GFER 1670/4885AXL 2184/4885MAPT 20/4885
US-11560518-B2 Polymerizable liquid crystal compound, polymerizable composition, polymer, retardation film, method for producing retardation film, transfer laminate, optical member, method for producing optical member, and display device TRRAP, CDH1, LRRFIP1 GFER 1670/4885AXL 2184/4885MAPT 20/4885
US-20210380884-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, TRANSFER LAMINATE, OPTICAL MEMBER, METHOD FOR PRODUCING OPTICAL MEMBER, AND DISPLAY DEVICE TRRAP, CDH1, LRRFIP1 GFER 1670/4885AXL 2184/4885MAPT 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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