Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.53 |
| ▸ | GAA | P10253 | 12/20 | 0.53 |
| ▸ | GLA | P06280 | 12/20 | 0.53 |
| ▸ | HPGD | P15428 | 9/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339237 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL20350815 | 0.77 | KDM4E (0.68) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL20339496 | 0.72 | KDM4E (0.70) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL20350855 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL20340123 | 0.70 | KDM4E (0.67) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL20339508 | 0.69 | KDM4E (1.00) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL562812 | 0.69 | KDM4E (1.00) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL20340016 | 0.68 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL20340182 | 0.68 | KDM4E (0.64) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL20340095 | 0.68 | KDM4E (0.77) | KDM4EALDH1A1GAAGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210379069-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S R L (IT) | 2021-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210379069-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | KDM4E 1110/4885ALDH1A1 171/4885GAA 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.