Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | PORCN | Q9H237 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408850 | 1.00 | WNT3A (0.38) | WNT3ADYRK1APORCNPSEN1PSEN2 | |
| SCHEMBL315085 | 0.86 | CYP11B2 (0.37) | WNT3ADYRK1APORCNPDK2ABL1 | |
| SCHEMBL315084 | 0.86 | CYP11B2 (0.37) | WNT3ADYRK1APORCNPDK2ABL1 | |
| SCHEMBL2411199 | 0.86 | ROCK1 (0.35) | ROCK1ROCK2ADORA3CYP3A4 | |
| SCHEMBL2411437 | 0.86 | GRM5 (0.37) | ROCK1ROCK2ADORA3CYP3A4 | |
| SCHEMBL2411194 | 0.86 | ROCK1 (0.35) | ROCK1ROCK2ADORA3CYP3A4 | |
| SCHEMBL2412695 | 0.86 | PRMT5 (0.40) | WNT3AABL1ADORA3PIK3CBCYP3A4 | |
| SCHEMBL2412704 | 0.86 | PRMT5 (0.40) | WNT3AABL1ADORA3PIK3CBCYP3A4 | |
| SCHEMBL2411434 | 0.86 | GRM5 (0.37) | ROCK1ROCK2ADORA3CYP3A4 | |
| SCHEMBL2408725 | 0.85 | MGLL (0.37) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013010-B2 | 5-thioxylopyranose compounds | LABORATOIRES FOURNIER S.A. (FR) | 2011-09-06 | — | — | US | disclosed |
| US-20090186840-A1 | 5-Thioxylopyranose Compounds | LABORATOIRES FOURNIER S.A (FR) | 2009-07-23 | — | — | US | disclosed |
| EP-2066681-A1 | NEW DERIVATIVES OF 5-THIOXILOPYRANOSE | LABORATOIRES FOURNIER SA (FR) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008037923-A1 | NEW DERIVATIVES OF 5-THIOXILOPYRANOSE | LABORATOIRES FOURNIER S.A. (FR) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186840-A1 | 5-Thioxylopyranose Compounds | TPMT, PNPO, CYP3A5 | WNT3A 3031/4885DYRK1A 4436/4885PORCN 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.