Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407875 | 0.73 | ALDH1A1 (0.52) | KMT2ATSHRSMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL6360331 | 0.73 | TSHR (0.59) | KMT2ATSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2408392 | 0.72 | HDAC1 (0.58) | KMT2ATSHRSMN1; SMN2HDAC2HDAC8 | |
| SCHEMBL2413988 | 0.72 | HDAC1 (0.56) | KMT2ASMN1; SMN2NPC1RAB9AHDAC2 | |
| SCHEMBL2408859 | 0.72 | HDAC1 (0.56) | KMT2ASMN1; SMN2NPC1RAB9AHDAC2 | |
| SCHEMBL8854765 | 0.71 | GAA (0.70) | KMT2ATSHRSMN1; SMN2GAAMAPT | |
| SCHEMBL2408884 | 0.71 | ALDH1A1 (0.46) | TSHRNPC1RAB9AHDAC2HDAC8 | |
| SCHEMBL29411444 | 0.71 | TSHR (0.72) | KMT2ATSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL21045493 | 0.71 | TSHR (0.72) | KMT2ATSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6570625 | 0.70 | RAB9A (0.70) | KMT2ASMN1; SMN2NPC1RAB9AHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |