Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | TP53 | P04637 | 8/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24089689 | 0.88 | MAPT (0.47) | MAPTTP53THRBKDM4ERECQL | |
| SCHEMBL21037254 | 0.82 | MEN1 (0.45) | MAPTKDM4ERECQLMEN1ALDH1A1 | |
| SCHEMBL24089680 | 0.80 | APP (0.38) | MAPTTP53THRBKDM4EMEN1 | |
| SCHEMBL24089831 | 0.79 | LMNA (0.60) | MAPTTP53THRBKDM4ERECQL | |
| SCHEMBL21037329 | 0.78 | MAPT (0.48) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL24089660 | 0.75 | RPS6KA3 (0.32) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL21037409 | 0.74 | L3MBTL1 (0.36) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL21037855 | 0.74 | APP (0.35) | MAPTMEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL24089762 | 0.73 | ALDH1A1 (0.50) | MAPTTP53KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL22314205 | 0.73 | APP (0.41) | MAPTKDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210382060-A1 | FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF | Shanghai Glory Capital Management Ltd. (CN) | 2021-12-09 | — | — | US | disclosed |