Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAT2A | P31153 | 4/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23065259 | 0.92 | ALDH1A1 (0.48) | ALDH1A1ALOX12MAT2AGRM1PRMT5 | |
| SCHEMBL24090095 | 0.92 | PIK3CD (0.50) | PIK3CDALOX12CYP1A2METAP2MDM2 | |
| SCHEMBL24111022 | 0.90 | PIK3CD (0.42) | PIK3CDGRM1HTR7CYP1A2TDO2 | |
| SCHEMBL30103245 | 0.89 | PIK3CD (0.50) | PIK3CDALDH1A1ALOX12CYP1A2METAP2 | |
| SCHEMBL23958245 | 0.89 | PIK3CD (0.50) | PIK3CDALDH1A1ALOX12CYP1A2METAP2 | |
| SCHEMBL29623145 | 0.87 | ALDH1A1 (0.48) | ALDH1A1ALOX12MAT2APRMT5MDM2 | |
| SCHEMBL24089900 | 0.87 | ALDH1A1 (0.48) | ALDH1A1ALOX12MAT2APRMT5MDM2 | |
| SCHEMBL24089988 | 0.87 | PIK3CD (0.46) | PIK3CDALDH1A1ALOX12HTR7CYP1A2 | |
| SCHEMBL24110982 | 0.87 | PIK3CD (0.43) | PIK3CDHTR7 | |
| SCHEMBL24089943 | 0.86 | PIK3CD (0.47) | PIK3CDALOX12CYP1A2METAP2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352366-B2 | 2-aminoquinazolinone derivative | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-06-07 | — | — | US | disclosed |
| US-20220143020-A1 | 2-AMINOQUINAZOLINONE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2022-05-12 | — | — | US | disclosed |
| US-20210380598-A1 | 2-AMINOQUINAZOLINONE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143020-A1 | 2-AMINOQUINAZOLINONE DERIVATIVE | CNKSR1, HAX1, CRKL | PIK3CD 4554/4885ALDH1A1 645/4885ALOX12 3008/4885 |
| US-20210380598-A1 | 2-AMINOQUINAZOLINONE DERIVATIVE | CNKSR1, HAX1, SLC26A3 | PIK3CD 4497/4885ALDH1A1 739/4885ALOX12 3295/4885 |
| US-11352366-B2 | 2-aminoquinazolinone derivative | CNKSR1, HAX1, SLC26A3 | PIK3CD 4497/4885ALDH1A1 739/4885ALOX12 3295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.