Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2415887 | 0.94 | HTR2C (0.34) | HTR2CSLC6A4RXFP1KAT8F2 | |
| SCHEMBL2411933 | 0.92 | HTR2C (0.33) | HTR2CSLC6A4RXFP1KAT8F2 | |
| SCHEMBL2408489 | 0.92 | HTR2C (0.36) | HTR2CSLC6A4RXFP1KAT8F2 | |
| SCHEMBL4420269 | 0.91 | HTR6 (0.37) | HTR2CSLC6A4KAT8F2HTR2A | |
| SCHEMBL2407588 | 0.90 | MET (0.38) | HTR2CSLC6A4KAT8F2KAT6A | |
| SCHEMBL2409254 | 0.89 | F2 (0.34) | HTR2CSLC6A4KAT8F2HTR2A | |
| SCHEMBL2411540 | 0.89 | MET (0.41) | F2 | |
| SCHEMBL5002713 | 0.88 | RXFP1 (0.35) | RXFP1MEN1KMT2A | |
| SCHEMBL2408606 | 0.88 | TDP1 (0.37) | HTR2CSLC6A4RXFP1MEN1KMT2A | |
| SCHEMBL2410115 | 0.88 | RORC (0.38) | KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |