Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2418766 | 0.92 | PTGDR (0.35) | ALDH1A1PKMTSHRPTGDR2KMT2A | |
| SCHEMBL2415722 | 0.91 | PTGDR2 (0.35) | SMN1; SMN2PTGDR2CCKARKMT2A | |
| SCHEMBL2412871 | 0.88 | PTGDR2 (0.42) | PDE4ANAMPTPTGDR2CCKAR | |
| SCHEMBL1278109 | 0.88 | FPR1 (0.34) | ALDH1A1SMN1; SMN2GAATSHRPTGDR2 | |
| SCHEMBL2416815 | 0.88 | GRM4 (0.33) | ADAMTS4PKMPTGDR2CCKAR | |
| SCHEMBL2414117 | 0.88 | APLNR (0.36) | NAMPTADAMTS4PTGDR2 | |
| SCHEMBL2412419 | 0.87 | GRM4 (0.39) | ALDH1A1SMN1; SMN2NAMPTNPSR1TSHR | |
| SCHEMBL1278409 | 0.86 | PTGDR2 (0.32) | NAMPTPTGDR2CCKAR | |
| SCHEMBL2412112 | 0.85 | KAT6A (0.32) | ALDH1A1SMN1; SMN2NAMPTTSHRPTGDR2 | |
| SCHEMBL2413126 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |