Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.62 |
| ▸ | CCR3 | P51677 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9536512 | 0.80 | CXCR4 (0.59) | CXCR4CCR3ACHE | |
| SCHEMBL6747206 | 0.78 | CXCR4 (0.65) | CXCR4CCR3ACHE | |
| SCHEMBL3934500 | 0.78 | KCNA3 (0.59) | SIGMAR1 | |
| SCHEMBL7501904 | 0.78 | DRD2 (0.63) | CXCR4CCR3SIGMAR1ACHE | |
| SCHEMBL8707233 | 0.77 | CXCR4 (1.00) | CXCR4CCR3HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL9537230 | 0.77 | BCHE (0.63) | CXCR4CCR3ACHE | |
| SCHEMBL349053 | 0.76 | CCR3 (0.71) | CXCR4CCR3SIGMAR1ACHEALDH1A1 | |
| SCHEMBL8406869 | 0.76 | CXCR4 (0.75) | CXCR4CCR3HDAC8HDAC3HDAC4 | |
| SCHEMBL4854037 | 0.76 | GAA (0.64) | CXCR4CCR3ACHE | |
| Hydrochloric Acid SCHEMBL8825453 | 0.76 | BCHE (0.62) | CXCR4CCR3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629277-B2 | Styrenyl 1,2,4-oxadiazole compounds | Piramal Enterprises Limited (IN) | 2014-01-14 | — | — | US | disclosed |
| CN-103108867-A | Oxadiazole compounds, their preparation and use | PIRAMAL LIFE SCIENCES LTD | 2013-05-15 | — | — | CN | disclosed |
| US-20130005771-A1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Enterprises Limited (IN) | 2013-01-03 | — | — | US | disclosed |
| EP-2539327-A1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Enterprises Limited (IN) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011104680-A1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005771-A1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND USE | MCL1, OXA1L, ABL1 | CXCR4 131/4885CCR3 411/4885HDAC8 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.