SCHEMBL2409232

SCHEMBL2409232

O=C(c1ccccc1)c1ccc(-c2ccc(SN3C(=O)C=CC3=O)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ALDH1A1 P00352 5/20 0.46
ATM Q13315 4/20 0.46
HSP90AA1 P07900 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
TLR9 Q9NR96 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
PKM P14618 1/20 0.46
CCR6 P51684 1/20 0.46
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
SRD5A2 P31213 1/20 0.43
FAAH O00519 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3282322 0.76 RAB9A (0.64) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL13019488 0.75 RAB9A (0.82) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL197633 0.75 RAB9A (0.82) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL12757113 0.74 RAB9A (0.62) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL41657 0.73 RAB9A (0.78) RAB9ALMNAMAPTMEN1KMT2A
Benzene SCHEMBL28384085 0.73 RAB9A (0.78) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL29143580 0.73 RAB9A (0.78) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL13534566 0.73 RAB9A (0.78) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL28246134 0.73 RAB9A (0.78) RAB9ALMNAMAPTMEN1KMT2A
Benzophenone SCHEMBL28231198 0.73 RAB9A (0.78) RAB9ALMNAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3369751-A1 NOVEL PHOTOINITIATORS Coloplast A/S (DK) 2018-09-05 EP disclosed
US-10040902-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2018-08-07 US disclosed
EP-2638076-B1 NOVEL PHOTOINITIATORS COLOPLAST AS (DK) 2018-03-28 EP disclosed
US-9873786-B2 Synthetic composition and coating for cell culture CORNING INCORPORATED (US) 2018-01-23 US disclosed
US-9708425-B2 Routes to polyacrylates COLOPLAST A/S (DK) 2017-07-18 US disclosed
EP-2705142-B1 SYNTHETIC COMPOSITION AND COATING FOR CELL CULTURE. CORNING INC (US) 2016-08-10 EP disclosed
US-9399633-B2 Photoinitiators COLOPLAST A/S (DK) 2016-07-26 US disclosed
US-9371308-B2 Polymeric photoinitiators COLOPLAST A/S (DK) 2016-06-21 US disclosed
US-20160060243-A1 NOVEL PHOTOINITIATORS COLOPLAST A/S (DK) 2016-03-03 US disclosed
US-20160002400-A1 POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2016-01-07 US disclosed
EP-2638077-A1 NOVEL POLYMERIC PHOTOINITIATORS Coloplast A/S (DK) 2013-09-18 EP disclosed
EP-2638078-A1 NEW ROUTES TO POLYACRYLATES Coloplast A/S (DK) 2013-09-18 EP disclosed
US-20130059940-A1 POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2013-03-07 US disclosed
EP-2539374-A1 POLYMERIC PHOTOINITIATORS Coloplast A/S (DK) 2013-01-02 EP disclosed
WO-2012150475-A1 SYNTHETIC COMPOSITION AND COATING FOR CELL CULTURE. CORNING INCORPORATED (US) 2012-11-08 WO disclosed
US-20120282697-A1 SYNTHETIC COMPOSITION AND COATING FOR CELL CULTURE CORNING INCORPORATED 2012-11-08 US disclosed
WO-2012062333-A1 NOVEL POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2012-05-18 WO disclosed
WO-2012062332-A2 NOVEL PHOTOINITIATORS COLOPLAST A/S (DK) 2012-05-18 WO disclosed
WO-2012062334-A1 NEW ROUTES TO POLYACRYLATES COLOPLAST A/S (DK) 2012-05-18 WO disclosed
WO-2011103878-A1 POLYMERIC PHOTOINITIATORS COLOPLAST A/S (DK) 2011-09-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160060243-A1 NOVEL PHOTOINITIATORS UROD, PUF60, PPOX RAB9A 4022/4885LMNA 2235/4885MAPT 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.