Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22698825 | 0.84 | — | — | |
| SCHEMBL22667033 | 0.81 | — | — | |
| SCHEMBL19051885 | 0.80 | DGAT1 (0.32) | — | |
| SCHEMBL8081012 | 0.78 | LPL (0.31) | — | |
| SCHEMBL24092862 | 0.76 | MAPT (0.43) | KDM4EHSD17B10 | |
| SCHEMBL22551967 | 0.75 | NOS3 (0.41) | NOS3NOS2KDM4EHSD17B10 | |
| SCHEMBL16278109 | 0.75 | LPL (0.46) | NOS3NOS2 | |
| SCHEMBL183601 | 0.75 | LPL (0.46) | NOS3NOS2 | |
| SCHEMBL29730121 | 0.75 | LPL (0.46) | NOS3NOS2 | |
| SCHEMBL23635134 | 0.75 | PDGFRB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426653-B1 | BICYCLIC COMPOUNDS FOR DIAGNOSIS AND THERAPY | AC IMMUNE SA (CH) | 2021-12-15 | — | — | EP | disclosed |