Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 8/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12384628 | 0.90 | NPC1 (0.44) | NPC1GNAI3GNAO1GNAI1L3MBTL1 | |
| SCHEMBL24023954 | 0.85 | SIGMAR1 (0.42) | NPC1GNAI3GNAO1GNAI1L3MBTL1 | |
| SCHEMBL22874721 | 0.85 | GNAI3 (0.57) | NPC1GNAI3GNAO1GNAI1L3MBTL1 | |
| SCHEMBL20892956 | 0.84 | MEN1 (0.47) | NPC1L3MBTL1SIGMAR1MEN1KMT2A | |
| SCHEMBL21431247 | 0.82 | GAA (0.34) | SIGMAR1MEN1KMT2ATLR9TLR8 | |
| SCHEMBL18888304 | 0.82 | GNAI3 (0.67) | NPC1GNAI3GNAO1GNAI1L3MBTL1 | |
| SCHEMBL7919921 | 0.81 | NPC1 (0.48) | NPC1GNAI3GNAO1GNAI1L3MBTL1 | |
| SCHEMBL25075204 | 0.81 | NPC1 (0.50) | NPC1GNAI3GNAO1GNAI1L3MBTL1 | |
| SCHEMBL14549450 | 0.81 | MAPT (0.39) | NPC1GNAI3GNAO1GNAI1SIGMAR1 | |
| SCHEMBL2603232 | 0.80 | GAA (0.40) | NPC1GNAI3GNAO1GNAI1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707133-B1 | BTK INHIBITOR COMPOUNDS | LILLY CO ELI (US) | 2021-12-15 | — | — | EP | disclosed |