Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24092980 | 0.82 | NPC1 (0.50) | MAPTSIGMAR1MEN1KMT2ATLR9 | |
| SCHEMBL18161032 | 0.78 | GAA (0.33) | GAAMAPTOPRL1 | |
| SCHEMBL19999715 | 0.76 | KDM5A (0.33) | GAAMAPT | |
| SCHEMBL19239929 | 0.75 | PTPN1 (0.36) | GAAMAPTOPRL1HSD17B10 | |
| SCHEMBL12384628 | 0.75 | NPC1 (0.44) | GAAMAPTTLR9TLR8TLR7 | |
| SCHEMBL26316144 | 0.74 | DPP4 (0.32) | GAA | |
| SCHEMBL23551102 | 0.74 | ALOX15 (0.46) | OPRL1TLR9TLR8TLR7 | |
| SCHEMBL19239928 | 0.74 | KDM5A (0.32) | GAA | |
| SCHEMBL19041083 | 0.72 | GAA (0.33) | GAAOPRL1 | |
| SCHEMBL24684743 | 0.71 | GNAO1 (0.42) | OPRL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019191112-A1 | CEREBLON BINDERS FOR THE DEGRADATION OF IKAROS | C4 THERAPEUTICS, INC. (US) | 2019-10-03 | — | — | WO | disclosed |