Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510919 | 0.81 | ALDH1A1 (0.35) | — | |
| SCHEMBL3621633 | 0.81 | TSHR (0.47) | TSHRTDP1 | |
| SCHEMBL200996 | 0.73 | CYP2D6 (0.37) | TSHRTDP1 | |
| SCHEMBL1614539 | 0.69 | TSHR (0.35) | TSHRTDP1 | |
| SCHEMBL17464881 | 0.67 | TSHR (0.43) | TSHRTDP1 | |
| Isobutanol SCHEMBL2058213 | 0.63 | — | — | |
| SCHEMBL1681306 | 0.63 | TSHR (0.41) | TSHRTDP1 | |
| SCHEMBL746608 | 0.63 | ALDH1A1 (0.39) | — | |
| SCHEMBL746607 | 0.63 | MEN1 (0.39) | TSHRTDP1 | |
| SCHEMBL12822305 | 0.63 | TSHR (0.33) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539378-B1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | GRACE W R & CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2539379-B1 | AMIDE ESTER INTERNAL ELECTRON DONOR AND PROCESS | W R GRACE & CO -CONN (US) | 2017-09-06 | — | — | EP | disclosed |
| US-9441058-B2 | Procatalyst composition with substituted amide ester internal electron donor | W. R. Grace & Co.—Conn. (US) | 2016-09-13 | — | — | US | disclosed |
| EP-2545087-B1 | PROCATALYST COMPOSITION WITH SUBSTITUTED AMIDE ESTER INTERNAL ELECTRON DONOR | GRACE W R & CO (US) | 2016-06-22 | — | — | EP | disclosed |
| US-20140163184-A1 | Procatalyst Composition with Substituted Amide Ester Internal Electron Donor | W. R. GRACE & CO.-CONN. | 2014-06-12 | — | — | US | disclosed |
| US-8604144-B2 | Procatalyst composition with substituted amide ester internal electron donor | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| US-8551903-B2 | Amide ester internal electron donor and process | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-10-08 | — | — | US | disclosed |
| US-8466081-B2 | Halogenated amide ester and internal electron donor with same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-18 | — | — | US | disclosed |
| EP-2545087-A1 | PROCATALYST COMPOSITION WITH SUBSTITUTED AMIDE ESTER INTERNAL ELECTRON DONOR | Dow Global Technologies LLC (US) | 2013-01-16 | — | — | EP | disclosed |
| EP-2539379-A1 | AMIDE ESTER INTERNAL ELECTRON AND PROCESS | Dow Global Technologies LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120316299-A1 | Amide Ester Internal Electron Donor and Process | W. R. GRACE & CO.-CONN. | 2012-12-13 | — | — | US | disclosed |
| WO-2011106500-A1 | AMIDE ESTER INTERNAL ELECTRON AND PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2011106497-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2011106494-A1 | PROCATALYST COMPOSITION WITH SUBSTITUTED AMIDE ESTER INTERNAL ELECTRON DONOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
| CN-1863784-B | 2-naphthylimino-1,3-thiazine derivative | SHIONOGI & CO | 2010-11-17 | — | — | CN | disclosed |
| US-7482339-B2 | 2-Naphthylimino-1,3-thiazine derivative | SHIONOGI AND CO., LTD. (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20060281738-A1 | 2-Naphthylimino-1,3-thiazine derivative | SHIONOGI AND CO., LTD. (JP) | 2006-12-14 | — | — | US | disclosed |
| CN-1863784-A | 2-naphthylimino-1,3-thiazine derivative | SHIONOGI & CO (JP) | 2006-11-15 | — | — | CN | disclosed |
| EP-1659117-A1 | 2-NAPHTHYLIMINO-1,3-THIAZINE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2006-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | NAT10, NAT1, NAA50 | TSHR 759/4885TDP1 1375/4885 |
| US-20060281738-A1 | 2-Naphthylimino-1,3-thiazine derivative | NPM1, OXTR, CYP2S1 | TSHR 440/4885TDP1 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.