Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2405739 | 0.82 | RPS6KA3 (0.53) | NT5ERPS6KA3FGFR1ESR1ESR2 | |
| SCHEMBL22699767 | 0.82 | FGFR1 (0.62) | NT5ERPS6KA3FGFR1ESR1ESR2 | |
| SCHEMBL11916214 | 0.82 | FGFR1 (0.47) | RPS6KA3FGFR1HCAR1 | |
| SCHEMBL2411573 | 0.82 | YTHDC1 (0.49) | NT5ERPS6KA3FGFR1HPGDYTHDC1 | |
| SCHEMBL2408393 | 0.80 | RPS6KA3 (0.57) | NT5ERPS6KA3FGFR1ESR1ESR2 | |
| SCHEMBL2408819 | 0.78 | ESR1 (0.52) | NT5ERPS6KA3ESR1ESR2YTHDC1 | |
| SCHEMBL22411546 | 0.75 | DYRK1A (0.42) | NT5ERPS6KA3FGFR1HCAR1 | |
| SCHEMBL25015530 | 0.74 | RPS6KA3 (1.00) | NT5ERPS6KA3FGFR1JAK3BTK | |
| SCHEMBL17052498 | 0.74 | HCAR1 (0.43) | RPS6KA3FGFR1HCAR1 | |
| SCHEMBL6804444 | 0.73 | FGFR1 (0.55) | NT5ERPS6KA3FGFR1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | claimed |
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | disclosed |