SCHEMBL24095915

SCHEMBL24095915

CCCCCCNC(=O)NCC(=O)COc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.55
ALDH1A1 P00352 1/20 0.55
HTT P42858 1/20 0.55
TSHR P16473 1/20 0.54
RECQL P46063 1/20 0.54
PLA2G4B P0C869 4/20 0.53
ZDHHC2 Q9UIJ5 1/20 0.51
NAAA Q02083 1/20 0.50
EPHX2 P34913 1/20 0.49
PLA2G4A P47712 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24095886 0.83 MEN1 (0.56) TSHRRECQLPLA2G4BEPHX2PLA2G4A
SCHEMBL10599988 0.82 RECQL (0.77) TSHRRECQLZDHHC2NAAA
SCHEMBL14112030 0.82 RECQL (0.77) TSHRRECQLZDHHC2NAAA
SCHEMBL24095908 0.81 PLA2G4B (0.58) TSHRRECQLPLA2G4BPLA2G4A
SCHEMBL8366672 0.80 RECQL (0.79) TSHRRECQL
SCHEMBL28524130 0.79 ALOX15 (0.61) ALDH1A1TSHRRECQLPLA2G4BZDHHC2
SCHEMBL28822989 0.79 ALOX15 (0.61) ALDH1A1TSHRRECQLPLA2G4BZDHHC2
SCHEMBL28822931 0.79 ALOX15 (0.61) ALDH1A1TSHRRECQLPLA2G4BZDHHC2
SCHEMBL19786680 0.78 MGLL (0.68) ZDHHC2
SCHEMBL8707397 0.77 PLA2G4B (0.59) PLA2G4BPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021252640-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME SENDA BIOSCIENCES, INC. (US) 2021-12-16 WO disclosed