SCHEMBL8707397

SCHEMBL8707397

CCCCCCCCCCCCCCC(=O)COc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 19/20 0.59
PLA2G4A P47712 1/20 0.57
MEN1 O00255 1/20 0.54
ALPL P05186 1/20 0.54
ALPI P09923 1/20 0.54
ALPG P10696 1/20 0.54
KMT2A Q03164 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9650471 1.00 PLA2G4B (0.59) PLA2G4BPLA2G4AMEN1ALPLALPI
SCHEMBL1743419 0.98 PLA2G4B (0.57) PLA2G4BPLA2G4AMEN1ALPLALPI
SCHEMBL6247942 0.93 PLA2G4B (0.57) PLA2G4BPLA2G4AMEN1ALPLALPI
SCHEMBL8823910 0.87 LTA4H (0.62) PLA2G4BPLA2G4A
SCHEMBL7377075 0.85 NR5A1 (0.62) PLA2G4BPLA2G4A
SCHEMBL24095886 0.84 MEN1 (0.56) PLA2G4BPLA2G4AMEN1ALPLALPI
SCHEMBL13472198 0.83 KMT2A (0.57) PLA2G4BMEN1ALPLALPIALPG
SCHEMBL7916259 0.83 PLA2G4B (0.61) PLA2G4BPLA2G4A
SCHEMBL7592696 0.82 PLA2G4B (0.63) PLA2G4BPLA2G4AMEN1ALPLALPI
SCHEMBL8519575 0.81 CES2 (0.49) PLA2G4BPLA2G4AMEN1ALPLALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998033793-A1 α-AZACYCLOMETHYL BENZOTHIOPHENE AND α-AZACYCLOMETHYL BENZOFURANE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION SANOFI-SYNTHELABO (FR) 1998-08-06 WO disclosed