Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507635 | 0.81 | HPGD (0.68) | HPGDEPHX1ALDH1A1HTTKMT2A | |
| SCHEMBL24095849 | 0.81 | NPC1 (0.51) | THRATHRB | |
| SCHEMBL24095812 | 0.80 | HPGD (0.66) | HPGDEPHX1ALDH1A1HTTEPHX2 | |
| SCHEMBL24096055 | 0.79 | HPGD (0.60) | HPGDEPHX1ALDH1A1HTTKMT2A | |
| SCHEMBL24095827 | 0.78 | HPGD (0.56) | HPGDEPHX1ALDH1A1HTTEPHX2 | |
| SCHEMBL10014325 | 0.78 | NPC1 (0.57) | HPGDEPHX1ALDH1A1HTTKMT2A | |
| SCHEMBL24095847 | 0.77 | SIGMAR1 (0.67) | HPGDEPHX1ALDH1A1HTTEPHX2 | |
| SCHEMBL16270338 | 0.77 | SMN1; SMN2 (0.65) | HPGDEPHX1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL11035774 | 0.76 | EPHX2 (0.69) | HPGDEPHX1ALDH1A1HTTEPHX2 | |
| SCHEMBL7426776 | 0.76 | KMT2A (0.57) | KMT2ATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252640-A1 | ASPARAGINE DERIVATIVES AND METHODS OF USING SAME | SENDA BIOSCIENCES, INC. (US) | 2021-12-16 | — | — | WO | disclosed |