SCHEMBL24096325

SCHEMBL24096325

CCCCCCCC(=O)N[C@@H](/C=C/S(C)(=O)=O)CC(N)=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
MAPK1 P28482 1/20 0.45
DEGS1 O15121 1/20 0.45
ASAH1 Q13510 1/20 0.45
DNM1 Q05193 1/20 0.44
NOD1 Q9Y239 4/20 0.42
ASAH2 Q9NR71 1/20 0.41
SLC6A5 Q9Y345 2/20 0.40
THRB P10828 1/20 0.40
CETP P11597 1/20 0.40
PLA2G2C Q5R387 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
SOAT1 P35610 1/20 0.39
CPT2 P23786 1/20 0.39
CPT1A P50416 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26292097 0.90 FAAH (0.45) FAAHMEN1KMT2AMAPK1DEGS1
SCHEMBL26292099 0.86 DEGS1 (0.43) FAAHMEN1KMT2AMAPK1DEGS1
SCHEMBL24096040 0.82 FAAH (0.49) FAAHMEN1KMT2AMAPK1DEGS1
SCHEMBL24096030 0.82 EPHX1 (0.48) ASAH2CPT2CPT1ACPT1B
SCHEMBL24096210 0.81 FAAH (0.47) FAAHMEN1KMT2AMAPK1DEGS1
SCHEMBL24095894 0.81 FAAH (0.47) FAAHMEN1KMT2AMAPK1DEGS1
SCHEMBL24096280 0.81 FAAH (0.47) FAAHMEN1KMT2AMAPK1DEGS1
SCHEMBL24095695 0.81 FAAH (0.46) FAAHMEN1KMT2AMAPK1DEGS1
SCHEMBL24095718 0.81 FAAH (0.46) FAAHMEN1KMT2AMAPK1DEGS1
SCHEMBL24096083 0.81 FAAH (0.46) FAAHMEN1KMT2AMAPK1DEGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME SENDA BIOSCIENCES INC (US) 2023-07-27 US disclosed
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME SENDA BIOSCIENCES INC (US) 2023-07-27 US disclosed
WO-2021252640-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME SENDA BIOSCIENCES, INC. (US) 2021-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME ASNS, SI, NARS1 FAAH 3546/4885MEN1 433/4885KMT2A 4069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.