Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411890 | 1.00 | NAALAD2 (0.52) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL2410928 | 1.00 | NAALAD2 (0.52) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL7086369 | 0.84 | LMNA (0.48) | NAALAD2ALDH1A1MEN1KMT2ATSHR | |
| Succinic Acid SCHEMBL3145429 | 0.82 | FFAR3 (0.48) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL6054231 | 0.82 | ALDH1A1 (0.56) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL2331455 | 0.80 | — | — | |
| SCHEMBL381314 | 0.80 | — | — | |
| SCHEMBL7964223 | 0.79 | NAALAD2 (0.44) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL68460 | 0.78 | NAALAD2 (0.52) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL11307948 | 0.78 | TSHR (0.55) | NAALAD2ALDH1A1MEN1CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106546-A1 | A PROCESS FOR THE PREPARATION OF ROSUVASTATIN INTERMEDIATE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2011-09-01 | — | — | WO | disclosed |