SCHEMBL2409779

SCHEMBL2409779

Cc1ccc(NN(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 2/20 0.46
TDP1 Q9NUW8 3/20 0.44
ACHE P22303 1/20 0.44
ALDH1A1 P00352 3/20 0.43
TSHR P16473 1/20 0.43
LMNA P02545 2/20 0.42
POLB P06746 2/20 0.39
RAPGEF4 Q8WZA2 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CHRNA7 P36544 1/20 0.39
RAB9A P51151 3/20 0.38
MAPK1 P28482 1/20 0.38
GFER P55789 1/20 0.38
MCL1 Q07820 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22734874 0.80 MAPT (0.48) HPGDMEN1KMT2AMAPTTDP1
SCHEMBL22299882 0.77 ALDH1A1 (0.50) HPGDMEN1KMT2AMAPTTDP1
SCHEMBL20377494 0.76 KCNH3 (0.50) MEN1KMT2AMAPTACHEALDH1A1
SCHEMBL1767113 0.76 ALDH1A1 (0.46) HPGDMEN1KMT2AMAPTTDP1
SCHEMBL6835310 0.76 ALDH1A1 (0.58) HPGDMEN1KMT2AMAPTTDP1
SCHEMBL54929 0.74 TSHR (0.48) HPGDTDP1ALDH1A1TSHRLMNA
SCHEMBL8759611 0.74 ALDH1A1 (0.46) HPGDMEN1KMT2AMAPTTDP1
Hydrochloric Acid SCHEMBL1932913 0.72 KCNH3 (0.47) HPGDTDP1ALDH1A1TSHRLMNA
Hydrochloric Acid SCHEMBL6004888 0.72 KCNH3 (0.47) HPGDTDP1ALDH1A1TSHRLMNA
SCHEMBL2383994 0.72 TDP1 (0.52) HPGDMEN1KMT2AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1346717-B1 One-bottle dental bonding composition DENTSPLY SANKIN K K (JP) 2007-05-23 EP claimed
US-7129281-B2 One-bottle dental bonding composition DENTSPLY-SANKIN K.K. (JP) 2006-10-31 US claimed
US-20030187092-A1 One-bottle dental bonding composition DENTSPLY-SANKIN K.K. (JP) 2003-10-02 US claimed
EP-1346717-A1 One-bottle dental bonding composition DENTSPLY-SANKIN K.K. (JP) 2003-09-24 EP claimed
EP-0509516-B1 Dental restoration composition SANKIN IND CO (JP) 1997-03-26 EP claimed
EP-0509516-A2 Dental restoration composition SANKIN KOGYO KABUSHIKI KAISHA (JP) 1992-10-21 EP claimed
EP-0410287-A2 Polyphosphazene derivatives containing carbonyl groups and variously alkylated tertiary amino groups CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1991-01-30 EP claimed
EP-3508190-B1 LIGHT CURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2022-02-09 EP disclosed
EP-1454921-B1 RADICAL POLYMERIZATION CATALYSTS AND ADHESIVE KIT FOR DENTAL USE TOKUYAMA CORP (JP) 2021-07-28 EP disclosed
US-10828240-B2 Light curable composition TOKUYAMA DENTAL CORPORATION (JP) 2020-11-10 US disclosed
CN-106146851-B Photocurable composition and cured product containing same 信越化学工业株式会社 2020-10-23 CN disclosed
US-10731062-B2 Gas-generating material and micropump SEKISUI CHEMICAL CO., LTD. (JP) 2020-08-04 US disclosed
EP-2860167-B1 GAS GENERATING MATERIAL, AND MICROPUMP SEKISUI CHEMICAL CO LTD (JP) 2020-04-29 EP disclosed
WO-1991013913-A1 LIGHT-CURABLE ORTHODONTIC BRACKET ADHESIVE GINGI-PAK (US) 1991-09-19 WO disclosed
US-4741872-A Preparation of biodegradable microspheres useful as carriers for macromolecules THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1988-05-03 US disclosed
EP-0245820-A2 Biodegradable microspheres as a carrier for macromolecules The University of Kentucky Research Foundation (US) 1987-11-19 EP disclosed
US-4530783-A Unsaturated polyesters SNIAL RESINE POLIESTERE S.P.A. (IT) 1985-07-23 US disclosed
US-4202926-A Polymer curing system PPG INDUSTRIES, INC. (US) 1980-05-13 US disclosed
US-4179395-A LIQUID CRYSTALS FOR USE IN DISPLAYS GENERAL ELECTRIC COMPANY (US) 1979-12-18 US disclosed
US-4128497-A TRISAZO DYE GENERAL ELECTRIC COMPANY (US) 1978-12-05 US disclosed