Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9479616 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TSHRHSD17B10ALOX15MAPT | |
| SCHEMBL222247 | 0.78 | ALDH1A1 (0.65) | ALDH1A1TSHRHSD17B10ALOX15MAPT | |
| SCHEMBL65261 | 0.76 | ALDH1A1 (1.00) | ALDH1A1TSHRHSD17B10ALOX15MAPT | |
| SCHEMBL146321 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10ALOX15MAPT | |
| SCHEMBL2409779 | 0.76 | HPGD (0.46) | ALDH1A1TSHRMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1767117 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10ALOX15MAPT | |
| Hydrochloric Acid SCHEMBL9693558 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10ALOX15MAPT | |
| SCHEMBL20377494 | 0.74 | KCNH3 (0.50) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL8685601 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10ALOX15MAPT | |
| Hydrochloric Acid SCHEMBL10664947 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054178-A1 | 1,7, and 1,9-diarylpolymethine salts | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054178-A1 | 1,7, and 1,9-diarylpolymethine salts | NGLY1, QPCT, LPO | ALDH1A1 2196/4885TSHR 3029/4885HSD17B10 1965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.