Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406679 | 0.91 | PTGDR2 (0.34) | PTGDR2L3MBTL1CTSK | |
| SCHEMBL2414633 | 0.91 | PTGDR2 (0.32) | PTGDR2L3MBTL1CTSK | |
| SCHEMBL2410005 | 0.91 | PTGDR2 (0.34) | PTGDR2HTTL3MBTL1CTSK | |
| SCHEMBL2412644 | 0.90 | CHRM5 (0.35) | PTGDR2METHTTL3MBTL1CHRM5 | |
| SCHEMBL5002572 | 0.88 | PTGDR2 (0.39) | PTGDR2METHTTTRPM8P2RX7 | |
| Hydrochloric Acid SCHEMBL4417845 | 0.86 | PTGDR2 (0.31) | PTGDR2 | |
| SCHEMBL2415547 | 0.86 | PPME1 (0.35) | PTGDR2 | |
| SCHEMBL2410591 | 0.85 | PTGDR2 (0.33) | PTGDR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4427597 | 0.85 | CHRM5 (0.32) | PTGDR2L3MBTL1CHRM5CTSK | |
| SCHEMBL2410366 | 0.85 | ALDH1A1 (0.38) | PTGDR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |