Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412644 | 0.88 | CHRM5 (0.35) | ALDH1A1NPSR1LMNAMAPTHTT | |
| SCHEMBL5008713 | 0.88 | ALDH1A1 (0.38) | ALDH1A1RECQLPKMRAB9ANPSR1 | |
| SCHEMBL2417463 | 0.87 | PTGDR2 (0.31) | PTGDR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2410005 | 0.85 | PTGDR2 (0.34) | ALDH1A1MAPTHTTPTGDR2PDE4A | |
| SCHEMBL2414633 | 0.85 | PTGDR2 (0.32) | MAPTMAPK1TSHRPTGDR2PDE4A | |
| SCHEMBL2406679 | 0.85 | PTGDR2 (0.34) | NPSR1MAPTPTGDR2PDE4APDE4B | |
| SCHEMBL2409830 | 0.85 | PTGDR2 (0.39) | HTTPTGDR2 | |
| SCHEMBL2410591 | 0.85 | PTGDR2 (0.33) | NPSR1MAPTPTGDR2PDE4APDE4B | |
| SCHEMBL2416583 | 0.84 | CTSK (0.33) | ALDH1A1PTGDR2PDE4APDE4BPDE4C | |
| SCHEMBL2410365 | 0.83 | ALDH1A1 (0.35) | ALDH1A1RECQLPKMRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |