Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926644 | 0.81 | KMT2A (0.64) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL6570625 | 0.79 | RAB9A (0.70) | KMT2AMEN1MAPTHDAC1HDAC6 | |
| SCHEMBL2407648 | 0.76 | KMT2A (0.62) | KMT2AMEN1MAPTHDAC1HDAC6 | |
| SCHEMBL2412015 | 0.76 | HDAC1 (0.61) | KMT2AMEN1HDAC1HDAC6HDAC11 | |
| SCHEMBL31680510 | 0.76 | SMN1; SMN2 (0.88) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL19472833 | 0.76 | PLK1 (0.64) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL3031951 | 0.76 | RAB9A (0.65) | KMT2AMEN1MAPTHDAC1HDAC6 | |
| SCHEMBL19478605 | 0.75 | PLK1 (0.66) | KMT2AMEN1LMNANPC1AHR | |
| SCHEMBL24711273 | 0.75 | LMNA (0.86) | KMT2AMEN1MAPTHDAC1HDAC6 | |
| SCHEMBL3028816 | 0.75 | RAB9A (0.63) | KMT2AMEN1MAPTHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |