Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | PPME1 | Q9Y570 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LGMN | Q99538 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.30 |
| ▸ | FEN1 | P39748 | 2/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406674 | 0.92 | PTGDR2 (0.33) | NR3C2P2RX7PTGDR2LGMNPLCG1 | |
| SCHEMBL2410587 | 0.89 | PTGDR2 (0.33) | P2RX7PTGDR2LGMNPLCG1 | |
| SCHEMBL2414626 | 0.87 | PLCG1 (0.32) | NR3C2PIK3C3P2RX7PLCG1 | |
| SCHEMBL2412640 | 0.87 | PTGDR2 (0.33) | PIK3C3P2RX7PTGDR2LMNAMEN1 | |
| SCHEMBL2409999 | 0.87 | PTPN1 (0.33) | PTGDR2LMNAPLCG1 | |
| SCHEMBL2409826 | 0.86 | PTGDR2 (0.38) | GRM4NR3C2P2RX7PTGDR2CTSB | |
| SCHEMBL2410363 | 0.84 | PKM (0.35) | LMNAPLCG1 | |
| SCHEMBL2416580 | 0.84 | PLCG1 (0.31) | PLCG1 | |
| SCHEMBL4999119 | 0.83 | GRM4 (0.37) | GRM4PPME1NR3C2PIK3C3PTGDR2 | |
| Hydrochloric Acid SCHEMBL4427593 | 0.83 | PTGDR2 (0.31) | PTGDR2PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |