Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22226918 | 0.90 | USP30 (0.48) | USP30SRD5A1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL22226875 | 0.86 | HPGD (0.51) | USP30HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL22226788 | 0.84 | USP30 (0.42) | USP30SRD5A1KDM4EL3MBTL1MAPK1 | |
| SCHEMBL22226783 | 0.83 | GRM5 (0.44) | USP30SRD5A1POLBKMT2APIK3CD | |
| SCHEMBL22226001 | 0.81 | USP30 (0.42) | USP30SRD5A1KDM4EPOLBSIRT2 | |
| SCHEMBL28617165 | 0.80 | SCN9A (0.51) | ALDH1A1MEN1KMT2ASCN9ANPC1 | |
| SCHEMBL22207535 | 0.79 | USP30 (0.37) | USP30SRD5A1KDM4EGAAHSD17B10 | |
| SCHEMBL22226787 | 0.79 | SRD5A1 (0.38) | USP30SRD5A1POLBALDH1A1SIRT2 | |
| SCHEMBL22226786 | 0.79 | SRD5A1 (0.36) | USP30SRD5A1SIRT2SIRT1SCN9A | |
| SCHEMBL22227203 | 0.79 | USP30 (0.43) | USP30KDM4EL3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922247-A1 | 15-PGDH INHIBITOR | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-12-15 | — | — | EP | disclosed |