Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668925 | 0.83 | KDM4E (0.62) | NAPRTL3MBTL1KDM4ECYP1A2MAPT | |
| SCHEMBL12797894 | 0.80 | KMT2A (0.38) | L3MBTL1CYP1A2NPC1TSHRMEN1 | |
| SCHEMBL13568061 | 0.79 | L3MBTL1 (0.45) | L3MBTL1KDM4ECYP1A2MAPTALDH1A1 | |
| SCHEMBL13568063 | 0.79 | P2RX7 (0.47) | L3MBTL1KDM4ECYP1A2MAPTALDH1A1 | |
| SCHEMBL9370451 | 0.78 | MAPT (0.49) | NAPRTL3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL13925527 | 0.78 | — | — | |
| SCHEMBL6989753 | 0.78 | — | — | |
| SCHEMBL3110927 | 0.78 | SMN1; SMN2 (0.47) | L3MBTL1KDM4ECYP1A2MAPTALDH1A1 | |
| SCHEMBL27620072 | 0.78 | L3MBTL1 (0.44) | L3MBTL1KDM4ECYP1A2MAPTALDH1A1 | |
| SCHEMBL19323009 | 0.77 | L3MBTL1 (0.50) | NAPRTL3MBTL1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |