SCHEMBL9370451

SCHEMBL9370451

CCOC(=O)Cc1cccnc1F

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
MAPK1 P28482 1/20 0.47
TBXAS1 P24557 1/20 0.46
LMNA P02545 3/20 0.46
NAPRT Q6XQN6 1/20 0.45
PKM P14618 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NPC1 O15118 1/20 0.44
GLA P06280 1/20 0.44
TSHR P16473 1/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.42
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3595140 0.84 MAPT (0.48) MAPTMAPK1TBXAS1LMNAPKM
SCHEMBL6642153 0.81 MAPT (0.46) MAPTMAPK1TBXAS1LMNAPKM
SCHEMBL10132049 0.81 MAPT (0.52) MAPTMAPK1TBXAS1LMNAPKM
SCHEMBL7404210 0.81 PKM (0.41) MAPTTBXAS1LMNAPKMHPGD
SCHEMBL4061267 0.81 MAPT (0.52) MAPTMAPK1TBXAS1LMNAPKM
SCHEMBL3587106 0.81 MAPT (0.46) MAPTMAPK1TBXAS1LMNAPKM
SCHEMBL27563569 0.81 SMN1; SMN2 (0.47) MAPTMAPK1TBXAS1LMNANAPRT
SCHEMBL12897074 0.81 TSHR (0.59) MAPTMAPK1LMNANAPRTL3MBTL1
SCHEMBL20346354 0.81 L3MBTL1 (0.57) MAPK1LMNANAPRTL3MBTL1NPC1
Hydrochloric Acid SCHEMBL9753901 0.80 SMN1; SMN2 (0.46) MAPTMAPK1TBXAS1LMNANAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5356908-A Agriculture E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-18 US disclosed
EP-0393911-B1 Fungicidal oxazolidinones DU PONT (US) 1994-08-31 EP disclosed
US-5223523-A Agriculture E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-29 US disclosed
EP-0533734-A1 FUNGICIDAL IMINOOXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-31 EP disclosed
WO-1991019703-A2 FUNGICIDAL IMINOOXAZOLIDINONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-26 WO disclosed
EP-0393911-A1 Fungicidal oxazolidinones E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-24 EP disclosed