Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411399 | 0.93 | HTR2C (0.31) | HTR2CSLC6A4HTR2ASSTR4 | |
| SCHEMBL2408854 | 0.91 | NFE2L2 (0.34) | HTR2CSLC6A4HTR2A | |
| SCHEMBL2410515 | 0.91 | HTR2C (0.33) | HTR2CSLC6A4HTR2ASSTR4RIPK1 | |
| SCHEMBL5008445 | 0.88 | DHODH (0.32) | — | |
| SCHEMBL2414689 | 0.87 | RIPK1 (0.35) | HTR2CSLC6A4HTR2ASSTR4RIPK1 | |
| SCHEMBL1830758 | 0.87 | HTR2C (0.34) | HTR2CSLC6A4HTR2ASSTR4 | |
| SCHEMBL1834426 | 0.86 | HTR2C (0.33) | HTR2CSLC6A4HTR2ASSTR4RIPK1 | |
| SCHEMBL1834859 | 0.86 | SSTR4 (0.33) | HTR2CSLC6A4HTR2ASSTR4 | |
| SCHEMBL4420269 | 0.85 | HTR6 (0.37) | HTR2CSLC6A4HTR2A | |
| Hydrochloric Acid SCHEMBL4414505 | 0.85 | KAT6A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |