Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.38 |
| ▸ | MC3R | P41968 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 6/20 | 0.37 |
| ▸ | NOS3 | P29474 | 3/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24101006 | 1.00 | MC4R (0.38) | MC4RMC3RNOS2NOS3NOS1 | |
| SCHEMBL25021306 | 0.95 | MC4R (0.35) | MC4RMC3RNOS2NOS3NOS1 | |
| SCHEMBL25021254 | 0.89 | NOS2 (0.35) | MC4RMC3RNOS2NOS3NOS1 | |
| SCHEMBL24506989 | 0.89 | NOS2 (0.37) | MC4RMC3RNOS2NOS3NOS1 | |
| SCHEMBL24100754 | 0.88 | LMNA (0.38) | MC4RMC3RNOS2NOS3NOS1 | |
| SCHEMBL24100183 | 0.87 | ACE (0.43) | MC4RMC3RMMEACECPA1 | |
| SCHEMBL25021304 | 0.87 | NOS2 (0.37) | MC4RMC3RNOS2NOS3NOS1 | |
| SCHEMBL25021945 | 0.83 | NOS2 (0.35) | MC4RMC3RNOS2NOS3NOS1 | |
| SCHEMBL24100557 | 0.83 | LMNA (0.44) | MC4RMC3RNOS2NOS3NOS1 | |
| Melphalan Flufenamide SCHEMBL24101233 | 0.82 | LMNA (0.53) | MC4RMC3RNOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210388024-A1 | COMPOUNDS CONTAINING DEUTERIUM | ONCOPEPTIDES AB (SE) | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210388024-A1 | COMPOUNDS CONTAINING DEUTERIUM | DHX30, H1-10, REN | MC4R 250/4885MC3R 178/4885NOS2 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.