Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.62 |
| ▸ | NPC1 | O15118 | 9/20 | 0.61 |
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24101684 | 0.84 | NPC1 (0.80) | SMN1; SMN2NPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL24101687 | 0.82 | LCK (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL24101792 | 0.80 | RAB9A (0.54) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL24101689 | 0.79 | NPC1 (0.73) | SMN1; SMN2NPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL24101794 | 0.78 | ALDH1A1 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL24101796 | 0.75 | ALDH1A1 (0.56) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL11025335 | 0.69 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL13342029 | 0.68 | F2 (0.71) | SMN1; SMN2NPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL3585075 | 0.68 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9ARXFP1ALDH1A1 | |
| SCHEMBL774617 | 0.67 | LCK (0.56) | SMN1; SMN2NPC1RAB9ARXFP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249517-A1 | A MOLECULAR GLUE REGULATING CDK12-DDB1 INTERACTION TO TRIGGER CYCLIN K DEGRADATION | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-12-16 | — | — | WO | disclosed |