Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24101687 | 0.81 | LCK (0.52) | ALDH1A1RAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL24101792 | 0.79 | RAB9A (0.54) | ALDH1A1RAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL24101795 | 0.78 | SMN1; SMN2 (0.62) | ALDH1A1RAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL24101796 | 0.76 | ALDH1A1 (0.56) | ALDH1A1RAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL4397896 | 0.75 | PKM (0.83) | ALDH1A1RAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL3587905 | 0.74 | PKM (1.00) | ALDH1A1RAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL93095 | 0.74 | ALDH1A1 (0.75) | ALDH1A1RAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL3587473 | 0.71 | KDM4E (0.81) | ALDH1A1RAB9ASMN1; SMN2NPC1HTT | |
| SCHEMBL3589722 | 0.69 | LCK (0.71) | ALDH1A1RAB9ASMN1; SMN2NPC1PKM | |
| SCHEMBL773591 | 0.68 | LCK (1.00) | ALDH1A1RAB9ASMN1; SMN2NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021249517-A1 | A MOLECULAR GLUE REGULATING CDK12-DDB1 INTERACTION TO TRIGGER CYCLIN K DEGRADATION | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-12-16 | — | — | WO | disclosed |